In what instances is a DEA Form 222 required?

A DEA Form 222 is specifically required for the distribution, purchase, or transfer of controlled substances classified as Schedule I or II. This requirement is in place because these substances have a high potential for abuse and are strictly regulated. The Form 222 serves as an official record of transactions involving these drugs, helping to maintain proper oversight and accountability within the pharmaceutical supply chain.

The completion of a DEA Form 222 ensures that all parties involved in the transaction are documented, which aids in preventing diversion and misuse of these potent medications. It is an important part of regulatory compliance for pharmacies and other entities that handle controlled substances, ensuring that their activities align with the legal framework established by the Drug Enforcement Administration (DEA).

In scenarios such as personal use of controlled substances or emergency refills, a DEA Form 222 is not required because these situations typically do not involve the transfer, sale, or distribution of Schedule I or II drugs in the same regulated context as required by the DEA. Similarly, patient prescription requests are part of a different operational process and do not necessitate the use of this specific form.