Which of the following actions must a pharmacist avoid when handling controlled substance prescriptions?

Pharmacists have a critical role in ensuring the safe and legal distribution of controlled substances. One key aspect of this responsibility is the handling of prescriptions in a manner that complies with the law and professional ethics. Making unauthorized changes to a prescription compromises both the integrity of the physician's order and the patient's safety.

When a pharmacist alters a prescription without authorization from the prescriber, it can lead to several issues. First, it may violate state and federal regulations concerning controlled substances, which mandate that prescriptions must reflect the prescriber's clear intent. Second, unauthorized modifications can pose direct risks to patient health, as changes might lead to inappropriate dosing or treatment regimens. Furthermore, such actions can jeopardize a pharmacist's license and lead to legal consequences.

Therefore, abstaining from making unauthorized changes is fundamental in maintaining the trust between pharmacists, patients, and prescribers, while ensuring compliance with legal standards surrounding the management of controlled substances.